Origin
Shiitake, or Black Forest mushrooms (Lentinus edodes), are fungi that grow on the trunks and stumps of trees, just like reishi mushrooms. Usually, it is the extract of the mycelia stage, or the immature growing stage of the shiitake mushroom that is used, having been recognized by Japanese scientists for its effectiveness in treating cancer. Key therapeutic compounds of the mycelia stage of the mushroom appear to be a new peptidomannan known as KS-2, and a water soluble lignin derivative known as EPS-3
Uses
The mushrooms are used to moderate high blood pressure and heart disease, reduce blood cholesterol, strengthen the immune system, treat viral infections, and ease fatigue. They are used with diabetic patients for the control of cholesterol, and in HIV infections because of their powerful immune support, which is active on four different levels: by increasing the activity of macrophages and T-cells; by boosting interleukin production; by augmenting the numbers of B-lymphocytes; and by intensifying antibody production. They seem to be also effective in treating cancer.
Caution
No cases of toxicity have been reported.