Pyridoxine is still another water-soluble vitamin of the B complex, consisting of a group of three naturally occurring compounds called pyridines, with different physiological functions. Vitamin B6, acting as the coenzyme form of Pyridoxal-5-Phosphate, may be involved in more functions of the human organism than most other nutrients. A short list of its known functions has as follows:

  • Amino acid, fat and carbohydrate metabolism
  • Anti-allergic and anti-depressant activity
  • Formation of red blood cells and antibody production
  • Important for smooth brain function
  • Indispensable for nerve impulse transmitters
  • Reduction of premenstrual syndrome effects
  • Synthesis of RNA and DNA, etc

Best food sources are dried brewer's yeast, wheat bran and yeast extract. Other sources are wheatgerm, oatflakes, soya flour, bananas, nuts, meats, fatty fish, walnuts, brown rice, potatoes and other vegetables.


  • Anemia
  • Bronchial asthma
  • Contraceptive pill depression
  • Control of toxic homocysteine in the blood reducing the risk of cardiovascular disease
  • Face skin lesions
  • Infantile convulsions
  • Morning and travel sicknesses
  • Premenstrual stress
  • Radiation sickness Deficiency
  • Atherosclerosis
  • Breast discomfort
  • Inflamed tongue and nerve ends
  • Irritability and mild depression
  • Kidney stones
  • Migraine
  • Puffy ankles and fingers
  • Splitting of lips
  • Swollen abdomen

When taken for long periods of time, or by persons with liver disease, pyridoxine should be preferably in the form Pyridoxal-5-Phosphate. Dosages, particularly in pregnancy, should be supervised by competent health professionals. Asthma, convulsions, premenstrual stress and urticaria may require high doses. But dosages of pyridoxine over 300mg a day have not been sufficiently investigated. And pyridoxine has a history of severe disability at very high doses.